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POLYCOMB REPRESSIVE COMPLEX 1
Descriptors Found:
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DeCS
Descriptor
English
:
Polycomb Repressive Complex 1
Descriptor
Spanish
:
Complejo Represivo Polycomb 1
Descriptor
Portuguese
:
Complexo Repressor Polycomb 1
Tree Number:
D05.500.781.100
D08.811.464.938.750.280
D12.776.660.235.600.100
D12.776.664.235.800.100
D12.776.930.780.890.100
Definition
English
:
A multisubunit polycomb protein complex with affinity for
CHROMATIN
that contains methylated HISTONE H3. It contains an E3
ubiquitin
ligase activity that is specific for HISTONE H2A and works in conjunction with
POLYCOMB REPRESSIVE COMPLEX 2
to effect
EPIGENETIC REPRESSION.
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54921
Unique Identifier:
D063150
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS